مقایسه اثرات 12 هفته تمرینات مقاومتی و استقامتی بر ANP، اندوتلین-1، آپلین و فشارخون در مردان میان‌سال با فشارخون بالا

Background & Aims: The purpose of this study was to compare the effects of 12-weeks of endurance and resistance training on ANP, Endothelin-1, Apelin and blood pressure in hypertensive middle-aged men. Materials & Methods: Twenty eight middle-aged men (age= 39.3±2.4 years and BMI= 28.6±1.7 kg/m2) with hypertensive volunteered to participate in this study and were randomly divided into two groups of 14 people taking the resistance and endurance. The training protocol consisted of endurance training with gradually increasing of duration and intensity and resistance training with 80% of the 1RM 3 times a week for 12 weeks. Fasting blood samples were measured before the start training protocol and 48 hour after last training sessions. Changes from baseline were assessed using the paired sample t-test and to determine comparisons between groups were analyzed with independent student’s t-tests. Results: In both endurance and resistance groups significant increase were observed at the post-test in ANP and Apelin and also significant decrease in Endothelin-1, systolic and diastolic blood pressure compared to pre-test. Moreover, the results showed that in the Endothelin-1, ANP and systolic blood pressure there were significant differences between groups in favor of the endurance group at the post-test. Conclusion: Although the implementation of endurance and resistance training for 12 weeks improves Apelin, Endothelin-1, ANP, systolic and diastolic blood pressure in hypertensive men, the rate of progress significantly improved in Endothelin-1, ANP and systolic blood pressure with endurance training. SOURCE: URMIA MED J 2016: 26(12): 1089 ISSN: 1027-3727